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Creative Biostructure, a biotech company specialized in providing contract services to both academia and biotech industries in the field of structural biology, recently updated its membrane protein service for customers in the pharmaceutical industry as well as institutions.

The cell membrane serves as the boundary of the cell, separating it from the external environment, and the membrane protein is the gateway of the cell. Nutrients, ions, waste, and even DNA and proteins are transported into and out of cells through membrane proteins. Membrane proteins are involved in many cellular functions, including: signal transduction, cell adhesion, cell movement, transportation, and cell communication. Given its important role in cell function, membrane proteins are often considered to be perfect drug targets. In fact, about two-thirds of the approved drugs target membrane proteins, however, these account for only a small percentage of potential targets. Therefore, membrane proteins are still the main focus of new drug discovery.

Scientists in Creative Biostructure has developed several efficient membrane protein expression systems and purification approaches to help solve the difficulties faced in drug charaterization and optimization.

Now several expression systems and purification approaches are available in Creative Biostructure, including:

Membrane protein expression systems

Cell based membrane protein expression
Cell free membrane protein expression (CFPS)
Protein detergent-free expression
Animal free recombinant protein expression
Plasma membrane protein isolation

Protein Purification

Chromatography

TFF/Diafiltration

Native protein purification

“As a leader in membrane production, Creative Biostructure provides membrane protein services from gene to structure with an emphasis on protein purification, crystallization, structure determination and analysis.” commented Joanna, the chief marketing staff in Creative Biostructure.

“We ensure that the native target structure is accurately determined at medium or high resolution. Based on comprehensive structural analysis, we further provide antibody development, drug discovery and vaccine formulation development.” added Joanna.

Besides, Creative Biostructure also provides a list of membrane proteins. If you want to know more detailed information, please visit https://www.creative-biostructure.com/custom-membrane-protein-services_25.htm.

About Creative Biostructure

Creative Biostructure is specialized in providing contract services to both academia and biotech/pharmaceutical industries in the field of structural biology. The company offers insightful strategies and cost-effective services on structure determination of macromolecules using X-ray Crystallography, EM, NMR, etc.