Press Releases

Creative Peptides Provides Synthetic Peptides for Developing Vaccines

In the current COVID-19 pandemic, synthetic peptides play an important role in vaccine development. Creative Peptides, a supplier mainly engaged in the production of biologically active peptides, recently announced that it can provide synthetic peptides for vaccine development.

Coronavirus contains at least four structural proteins, namely spike protein (S), envelope protein (E), membrane protein (M) and nucleocapsid protein (N). The main function of the nucleocapsid protein (N) is to package the viral RNA genome in the virus envelope into a ribonucleoprotein (RNP) complex called the capsid. In addition, the N protein of SARS-CoV-2 affects the response of host cells and may play a regulatory role in the virus life cycle. Creative Peptides provides SARS-CoV-2 Nucleoprotein, SARS-CoV-2 Spike glycoprotein, and SARS-CoV-2 Membrane protein and other peptide products that can be used in vaccine research and immunoassay development.

RGD peptide is a tripeptide sequence composed of L-arginine, glycine and L-aspartic acid, which is a common element in cell recognition. RGD peptide is the binding motif of fibronectin and cell adhesion molecules. RGD peptides can act as inhibitors of integrin-ligand interactions, and induce apoptosis in the absence of signal and integrin-mediated cell clusters.

Antimicrobial peptides are a variety of natural molecules, also called host defense peptides, which are produced by all multicellular organisms as the first line of defense. Antimicrobial peptides have been proven to kill Gram-negative and Gram-positive bacteria, enveloped viruses, fungi, and even cancer cells. Natural AMP is unstable, has a short half-life, has some toxic and side effects, and may also have serious hemolytic activity. Therefore, in order to apply AMP to the clinic, it is necessary and important to develop stable and durable AMP analogs.

FLAG peptide is an eight amino acid peptide (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys) with an enterokinase-cleavage site. It is designed for antibody-mediated identification and purification of recombinant proteins. 3X FLAG Peptide is a synthetic peptide with a 3-time repeated DYKXXD motif.

Angiotensin is composed of at least three polypeptide hormones: Angiotensin I (Ang I), Angiotensin II (Ang II) and Angiotensin III (Ang III). Angiotensin I is derived from a protein secreted by the liver through the action of renin. Ang II is an effective blood pressure regulator, which can regulate blood pressure and maintain total blood volume and salt homeostasis. It controls the release of antidiuretic hormone (ADH) and aldosterone. Angiotensin II is the precursor of angiotensin III, which in turn stimulates the release of aldosterone from the adrenal glands. Angiotensin II not only plays an important role in the etiology of hypertension, but also plays an important role in the pathophysiology of human cardiovascular diseases.

Creative Peptides has developed a wide range of products and services for scientists to accelerate the development of drugs and vaccines for COVID-19 / SARS-CoV-2. For more information, please visit the website: https://www.creative-peptides.com/covid-19-services-and-products.html.

About Creative Peptides

As a US-based expert aimed at creating a better and healthier world for the human beings together with concerted efforts from many industries, Creative Peptides keeps enriching its peptide related products and services in the last two decades, with a comprehensive product range covering cosmetic peptides, catalog peptides, checkpoint inhibitors, therapeutic peptides as well as a one-stop peptide synthesis, modification and analysis service, including Stapled Peptide Synthesis, Long Peptides Synthesis, Cyclic Peptide synthesis, Oligopeptide Synthesis, Post-translational Modification, Peptide Drug Discovery, Peptide Lead Optimization, etc.