Press Releases

Profacgen, a protein service provider with a wide category of custom services available from protein production, bioinformatic analysis, to different analysis during drug development, now provides an ultimate solution of cell-free protein production service for its customers worldwide.

Cell-free expression systems produce proteins in vitro through translational mechanisms extracted from cells. It has become an advanced technique for protein synthesis in cell lysates. This approach satisfies the growing demand for more direct, rapid and efficient protein production modalities.

Cell-free expression overcomes many of the barriers to conventional cellular expression. First, it is ideal for high-throughput mutagenesis screens. Moreover, the system works independently and has no cellular environment. The whole machine establishes a better environment for making toxic proteins, membrane proteins and proteins that are easily degraded by intracellular proteases. In addition, the reaction step can be simply controlled by adding/removing certain factors, such as cofactors, energy, detergents, etc.

Profacgen's cell-free protein expression service is a more efficient, rapid, and straightforward way to produce proteins that cannot be produced by conventional cellular expression. The cell-free expression system is ideal for high-throughput screening of mutagenesis.

Highlights:

• Can manufacture toxic proteins, membrane proteins, and proteins that would be easily degraded by intracellular proteases

• High-throughput protein expression

• Protein expression with proper post-translational modifications

Based on the information on Profacgen’s official website, different types of cell-free expression systems are used, including E. coli lysate, rabbit reticulocyte lysate (RRL), wheat germ lysate, insect cell lysate, and human cell lysate, depending on the purpose of the expressed protein.

“Our team of professionals has accumulated a substantial amount of experience in producing high-quality proteins using the cell-free protein expression system. We have completed many successful cases for our clients in the past. Our proteins can be expressed in small or large quantities, and our production process is always strictly controlled to produce the most reliable proteins.” commented Crystal, the chief marketing staff at Profacgen.

To know more detailed information about Profacgen’s cell-free protein expression system, please visit https://www.profacgen.com/Cell-free-protein-expression.htm.

About Profacgen

Profacgen provides process development and cGMP manufacturing services for biological active ingredients. We have ready access to state-of-the-art biopharmaceutical product development and manufacturing facilities and our staff scientists have demonstrable expertise in all aspects of biopharmaceutical manufacturing, from facility design and operation to the ability to provide best advice relating to product development.