HAYWARD, CA - Sep 20, 2018 - Paragon Genomics, Inc. today announced the launch of ParagonDesigner™, its web-based tool that enables rapid design of CleanPlex® Custom NGS Panels. The online portal features a streamlined, user-friendly interface that simplifies the assay design process, making it easy for researchers to build customized next-generation sequencing (NGS) assays addressing their specific needs. The custom panels are powered by Paragon Genomics' unique CleanPlex technology, an ultra-high multiplexed PCR-based target enrichment chemistry that makes it possible to include a large number of genomic targets in a single assay.

“ParagonDesigner allows our customers to build CleanPlex Custom NGS assays with just a few clicks of the mouse," said Tao Chen, founder and CEO of Paragon Genomics. "By combining our proprietary target enrichment chemistry and our advanced design algorithm in an assessible online tool, we make it easy for researchers and assay developers to design high quality NGS panels optimized to meet their needs. We provide the best hands-on expert support in the industry to all our customers, and we are proud of our rapid turnaround time-just two to four weeks."

Paragon Genomics design experts are available to provide hands-on personalized support to all ParagonDesigner customers, even for small orders. The company delivers custom NGS panels in 2 to 4 weeks. Other providers typically take six weeks or longer.

With ParagonDesigner, users define the content of their custom NGS assays by submitting their targets online. ParagonDesigner features a database of more than 1,300 pre-designed, clinically-relevant human genes, allowing CleanPlex Custom NGS Panels to be instantly assembled for most applications. The design tool also issues a report on the estimated panel size and design coverage for review prior to submission.

Paragon Genomics' CleanPlex technology is a proprietary, ultra-high multiplexed PCR-based target enrichment technology for NGS featuring an innovative PCR background cleaning chemistry that allows tens of thousands of amplicons to be multiplexed in a single pool of reaction, allowing a large number of targets to be interrogated in a single assay. The CleanPlex technology is combined with Paragon Genomics' advanced panel design algorithm to create optimized custom NGS assays tailored to the user's application and input type, ensuring high sequencing performance and assays that work the first time without further optimization. Users have designed CleanPlex Custom NGS Panels for a wide variety of applications, including tumor profiling, early cancer detection, high-throughput genotyping and gene expression analysis. CleanPlex Custom NGS Panels can be designed for sequencing on either Illumina or Ion Torrent platforms.

For more information about ParagonDesigner and CleanPlex Custom NGS Panels, visit www.paragongenomics.com/custom_panels.

Paragon Genomics’ CleanPlex® products are for Research Use Only.

About Paragon Genomics                                                                                              Paragon Genomics (paragongenomics.com) is a leader in amplicon-based target enrichment and library preparation solutions to accelerate the development of next-generation sequencing (NGS)-based assays for research and clinical testing. The company designs high performance and ultra-multiplexed amplicon NGS panels and develops NGS library preparation chemistries for analyzing difficult, clinically-relevant samples. It strives to make the design of custom NGS assays easily available to a broad range of users, with expert counsel and rapid turnaround. Privately-held Paragon Genomics is located in Hayward, California.