Creative Proteomics Launches Several Newly-developed Services for Protein Related Projects
Creative Proteomics, a leading supplier in proteomics and metabolomics services, has recently released several proteomics services to researchers. The service ranges include four: iTRAQ labeling service, label free quantitation service, SILAC mass spectrometry service, and TMT proteomics service.
Relative quantification of proteins that find biomarkers in complex mixtures by mass spectrometry can be easily and quickly achieved using iTRAQ labeling technology. “iTRAQ is ideal for comparing normal, diseased and drug treated samples, time course studies, biological replicates, and providing relative quantification. Creative Proteomics offers iTRAQ protein quantification services for unbiased, non-targeted biomarker discovery,” commented by vice president of Creative Proteomics.
SILAC-based quantitative proteomics (SILAQ) is an innovative technique for high-throughput quantitative analysis of large protein complexes, protein-protein and protein-small molecule interactions. Creative Proteomics' SILAC mass spectrometry service provides an unbiased strategy that reveals the effects of inhibitors or other perturbations on protein dynamics and cell distribution. It can also be used as a sensitive and efficient method for determining specific interaction partners for proteins in cells.
Label free quantification is a method in mass spectrometry that aims to determine the relative amount of protein in two or more biological samples. Unlike other protein quantification methods, label-free quantification does not use compounds containing stable isotopes to chemically bind and thus label proteins. Creative Proteomics provides a label-free approach for relative and absolute quantification, a fast and low-cost alternative to other quantitative proteomics methods.
The isobaric tag TMT has up to 11 tags that can be used to label almost any peptide or protein sample. TMT can reuse analysis, effectively utilize instrument time and further control technology changes. Because it is capable of up to 11 samples, TMT proteomics is widely used to quantify protein biomarker discovery. TMTzero, TMTduplex, TMTsixplex, TMT10plex and TMT11plex reagents share the same structure, allowing efficient conversion from method development to multiple quantification.
“Creative Proteomics is a professional biotech company specializing in providing Proteomics services. State-of-the-art equipment, highly trained and experienced staff, as well as reference methodologies are utilized to enable us to deliver consistent and high-quality data with cost-efficiency. Based on highly experienced and knowledgeable in the application of wine analysis, Creative Proteomics can provide fast turnaround, clear concise written reports, and custom service to help customers resolve your analytical and technical challenges.” said Dr. Charlie.
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