Creative Biogene, one of the top leading biotechnology products and services providers, has become the researchers’ one-stop shop for the advanced technology platforms they need to make advancements. In addition, Creative Biogene offers pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates. Recently, Creative Biogene announced the release of its high-performance CHO stable cell lines to support R&D development and cGMP commercial production.

With over 10 years of experience in stable cell line development, Creative Biogene has developed a proprietary High-Performance CHO Stable Cell Line Development (HP-CHO SCLD) platform for a wide range of applications from R&D development to cGMP commercial production. Based on years of innovation, Creative Biogene scientists are able to tailor the development process of each cell line to meet various customer needs and specific requirements. Creative Biogene is always available to help generate project-appropriate stable cell lines to support drug discovery, upstream or downstream bioprocessing.

The highlights of CHO cell lines offered by Creative Biogene:

Robust CHO-K1 Host Cell Line

Grow in suspension, allowing for large scale culture

Compatible with chemically defined commercial media, animal product-free culturing

Path to commercialization

Proprietary Expression Vectors

Optimized for CHO delivery and expression

Monocistronic, bicistronic vectors

Cell Line Development

Expressing diverse biologics with high-quality, mAbs, biosimilars, recombinant proteins, growth factors, bispecifics, etc.

Great performance in productivity, e.g., 6-8 g/L mAbs

Excellent cell line stability, over 30 generations

Creative Biogene also provides cell line characterization services, cell bank generation and process development services to support assay development and analysis, develop upstream and downstream processes for scalable production and technology transfer, traceable records from vector construction to cell line development, and support clinical trials and market authorization.

Creative Biogene offers a variety of assays to evaluate and select optimal single-cell clones with high productivity and stability, including Western Blot, PAGE, ELISA, HPLC etc.

“We offer services for generating stable cell lines that can overexpress virtually any protein of interest in the cell line of your choice.” said Marcia Brady, the marketing director of Creative Biogene, she also added, “we evaluate gene expression in stable cell clones by one or more assays and select the optimal strategy and corresponding vector system according to your requirements.”

About Creative Biogene

Creative Biogene is a top-of-its-kind company that holds a leading position and is committed to accelerating the development of human science through biotechnology, offering innovative technologies, products, unique tools, and services for research discoveries and product development. With more than 10 years of experience and in-house experts, Creative Biogene has become a well-recognized industry leader to support researchers worldwide.