Ringing in 2025 With Validating Novel Digital Clinical Measures, Decentralized Trials, and More
Jan 7, 2025
In this episode of the Scope of Things, host Deborah Borfitz delivers the news on an investigation into data reporting problems in major Ticagrelor clinical trial PLATO, the need for more sex-aware cancer research, Alzheimer’s studies looking at brain shrinkage associated with immunotherapies (and repurposing drugs as potential new treatments), and a large, decentralized trial that successfully uncovered disease-causing genetic variants in hundreds of participants. Benjamin Vandendriessche , chief delivery officer of Digital Medicine Society, also joins in to talk about a newly completed project with the FDA that is providing guidance and resources on how to validate novel digital clinical measures.
SHOW NOTES
News Roundup
PLATO trial investigation
- Findings published in The BMJ
“OncoSexome” project
- Paper in Nucleic Acids Research
Brain shrinkage with Alzheimer’s treatment
- Research in The Lancet Neurology
Repurposing drugs for Alzheimer’s
- Study in Alzheimer’s & Dementia
Mayo Clinic Tapestry study
- Article in Mayo Clinic Proceedings
Guest
Benjamin Vandendriessche, chief delivery officer, Digital Medicine Society
GUEST BIO
Benjamin Vandendriessche, Chief Delivery Officer, Digital Medicine Society
Benjamin (Ben) Vandendriessche is Chief Delivery Officer at the Digital Medicine Society, dedicated to advancing digital medicine to optimize human health. He has first-hand expertise in the development of and market access paths for regulated digital health technologies, and their medical applications in research and delivery of care. Previously, Ben was Chief Medical Officer at health tech startup Byteflies, to develop a remote patient monitoring platform for clinical trials and virtual care applications.
He trained in molecular biology, systems physiology, and data analytics for vital sign processing. He completed a PhD in Molecular Biology at Ghent University as an IWT Fellow, followed by a postdoc on the interface between Critical Care Medicine and Computer Science at Case Western Reserve University (CWRU) as a BAEF Fellow. He holds an adjunct assistant professor position at CWRU and publishes regularly on all things digital medicine.
