• Next Step Forward: PRA Named CRO for Leukemia & Lymphoma Society Global Master Clinical Trial

    Clinical Research News | Last month, the Leukemia & Lymphoma Society (LLS) and PRA Health Sciences announced their partnership in LLS’s first-of-its-kind global master clinical trial to develop new treatments for children with relapsed acute leukemia. The LLS PedAL (Pediatric Acute Leukemia) master clinical trial will simultaneously test multiple targeted therapies for children who experience a relapse of their acute leukemia. Now PRA has signed on as the contract research organization for the trial.

    Oct 5, 2020

  • Short-Lived Antibodies, Troubling Trends, Vitamin D, Delirium: COVID-19 Updates

    Clinical Research News | Case fatality rates among minorities questioned, vitamin D matters, ECMO saving lives, concerning genetic mutations, rise in anti-Asian racism, older adults excluded from trials, treatment potential of diabetes drug, rise in alcohol consumption, risks to mental health and men’s testosterone level, scary changes in care-seeking behavior, antibodies not eternal, pre-existing immunity may be widespread, younger cohorts dying in India, mostly men calling the shots, and delirium a key symptom among the elderly. Plus, a wealth of industry news that includes trials targeting nursing homes, launch of an eight-state patient data registry and an app to quantify mask-wearing behavior.

    Oct 2, 2020

  • ‘Hybrid’ Trials Will Be Post-Pandemic Norm

    Clinical Research News | For Medable, a leading advocate of decentralized clinical trials (DCTs), COVID-19 attracted surprising if welcome attention to the idea of making studies more patient-centric. The pandemic helped grow company revenues 400% in the first half of 2020 and, in the estimation of CEO and co-founder Dr. Michelle Longmire (a Stanford-trained physician), accelerated DCT adoption by five years.

    Sep 30, 2020

  • The Ongoing Impact of COVID-19 on Clinical Research

    Clinical Research News | In assessing the impact of COVID-19 on clinical research and development, companies are considering a range of factors including the ability of patients to access medicines and travel to trial sites, whether patients might decline to participate in clinical research, potential changes in regulatory guidance, and resource allocation at trial sites.

    Sep 28, 2020

  • New Patient Prediction Models From Hopkins, Mount Sinai, Two VA Studies, New Vax Trials: COVID-19 Updates

    Clinical Research News | Both Johns Hopkins and Mount Sinai release patient prediction models, Mass General publishes new blood test for patient stratification, two VA studies look at COVID-19 in vet populations, study shows widespread kidney damage with 30% of patients needing dialysis, and FDA issues a guidance for assessing COVID-19 symptoms in clinical trials. Plus, NIAID launches fourth clinical trial for a SARS-CoV-2 vaccine, NIH expands trials of convalescent plasma, and screening program launches for sub-Saharan Africa.

    Sep 25, 2020

  • Elsevier Launches SMART on FHIR Tool To Better Educate Patients

    Clinical Research News | Elsevier has launched PatientPass, a cloud-based patient engagement platform integrated with the Epic Electronic Health Record (EHR) system using SMART on FHIR. The new platform will let clinicians choose and deliver highly personalized, actionable content to patients in several formats, including on their mobile phones and via SMS alerts.

    Sep 22, 2020

  • Measuring Deaths and Long-Term Effects, Questions About Russian Vaccine, Citizen Scientists Making Their Own: COVID-19 Updates

    Clinical Research News | COVID-19 will become seasonal (eventually), mental effects on children and pregnant women, gaps in vaccine interest, what’s behind disparities, a test to identify plasma donors, better way to measure deaths, thousands could have lasting nerve damage, what does and doesn’t put people at higher risk, reasons for rehospitalization, potential shortening of life expectancy, azithromycin okay by itself, and researchers question Russian vaccine while citizen scientists experiment with DIY ones. Plus, a backlog in oncology, AI put to work and seven digital health solutions get NIH funding.

    Sep 18, 2020

  • Pandemic’s Silver Lining: Lasting Research Innovation

    Clinical Research News | While non-COVID medical research, including clinical trials, has partially resumed after widespread suspensions, delays and slowdowns during the outbreak, subsequent waves of COVID-19 infections still threaten to re-occupy clinicians, researchers, and labs. Fortunately, adversity can trigger adaptation.

    Sep 16, 2020