• 21st Century Cures Act Would Have Let Failed Alzheimer's Drugs Slip Through

    FierceBiotech |  The National Center for Health Research warns that the 21st Century Cures Act, now under consideration by Congress, would open substantial loopholes for ineffective drugs - reflecting on how three failed Alzheimer's drugs would have fared if the act had been in effect.

    Nov 24, 2015

  • The Importance of an eCOA Device Supply Strategy in Global Clinical Trials

    Clinical Informatics News | Contributed Commentary | Over the past decade, electronic Clinical Outcome Assessment (eCOA) has become increasingly popular in global clinical trials thanks to the technology’s ability to provide more complete data collection, boost compliance, and manage patients in real-time. Despite its proven record in supporting clinical trials of all sizes and complexities, many sponsors and CROs still have reservations about implementing eCOA. 

    Nov 23, 2015

  • Optimizing the Pipeline: Making Genomics In the Clinic a Reality

    Clinical Informatics News | Today HudsonAlpha held the grand opening for the Smith Family Clinic for Genomic Medicine, a collaboration between the HudsonAlpha Institute, the University of Alabama at Birmingham; and Children's of Alabama, a pediatric medical center.

    Nov 20, 2015

  • CLARITY Challenge Results Show Disparity in Reporting

    Clinical Informatics News | Results are in for the CLARITY Undiagnosed challenge, a crowdsourced competition sponsored by the Manton Center for Orphan Disease Research at Boston Children's and the Department of Biomedical Informatics (DBMI) at Harvard Medical School.

    Nov 18, 2015

  • Speeding Study Startup Through Better Collaboration and Data Flow

    Clinical Informatics News Contributed Commentary | A critical question facing many sponsors and contract research organizations is whether another system to support study startup is really needed. It’s a fair question in the clinical world where the urgent need for better execution of clinical trials has led to a proliferation of technologies, namely the clinical trial management system; the electronic trial master file; electronic data capture; and others. Each of these solutions focuses on specific pieces of the clinical trial continuum, yet, they overlook aspects unique to SSU, a complex process that continues to stumble and stall clinical trial timelines.

    Nov 16, 2015

  • Clinical Decision Alerts Poorly Tailored to Purpose in Opioid Prescriptions

    EHR Intelligence | A study in Annals of Emergency Medicine has shown that clinical decision alerts designed to prevent adverse events from opioids have extremely low specificity, presenting doctors with over 120 unnecessary alerts for every one adverse event prevented.

    Nov 13, 2015

  • Drug makers kept many clinical trial results a secret study

    Pharmalot |  In a study of 318 clinical trials, 35% of results were not disclosed. Glaxo, J&J, and Pfizer were the most transparent pharma companies, releasing all of the trial data for drugs approved in 2012. Gilead Sciences and Sanofi disclosed the least trials.

    Nov 12, 2015

  • Diagnostic Errors Test the Promise and Limitations of HIT

    Diagnostics World | Following a recent report from the Institute of Medicine that concludes most Americans will receive at least one misdiagnosis in their lifetimes, Drs. Hardeep Singh and Mark Graber have published recommendations in the New England Journal of Medicine for reforms, both technological and cultural, to address the issue of diagnostic error.

    Nov 12, 2015

  • EMC hospital to pay $90000 over stolen laptop with medical data

    Computerworld |  Medical data security gets expensive. EMC and Hartford Hospital have agreed to pay $90,000 to Connecticut for the loss in 2012 of an unencrypted laptop containing patient information of 8,883 residents of the state, according to the state's attorney general.

    Nov 9, 2015

  • Seven Major Cancer Centers to Pool Genetic and Health Data

    Xconomy |  A consortium of cancer centers, aided by Sage Bionetworks, is hoping that sharing health records and genetic testing results will demonstrate a clinical benefit to exploratory sequencing in cancer cases.

    Nov 9, 2015

  • Platform Integration Can Boost Pharmacovigilance

    Clinical Informatics News | Contributed Commentary There’s been a lot of talk within the industry about how integrating electronic data capture (EDC) platforms used within the clinical research industry with platforms used to create, manage and store electronic health records (EHR) could benefit physicians, healthcare institutions and pharmaceutical companies. But there is an additional benefit that directly impacts improvements in patient safety that has been less noticed: how EDC/EHR integration can actually make existing drugs, therapeutics and medical devices safer for patients.

    Nov 9, 2015

  • Bluebird Gene Therapy Trial Shows Promising but Nuanced Results

    TheStreet |  Bluebird Bio has released new interim results from its clinical trial of LentiGlobin gene therapy for beta-thalassemia and sickle cell disease, showing that it can wean patients off blood transfusions but that results are unexpectedly dependent on recipients' exact genotypes.

    Nov 5, 2015

  • Fixing The Healthcare Dichotomy

    TechCrunch |  Private industry and government alike are increasingly banking on APIs to resolve communication problems between electronic health records and other data silos in healthcare.

    Nov 4, 2015

  • Best Practices Call for Entries Open

    Clinical Informatics News | The third annual Clinical Informatics News Best Practices program is open for entries. The 2016 winners will be announced in February in Miami at the Summit for Clinical Ops Executives.

    Nov 4, 2015