• Targeted HIV Therapy Without Genotyping

    Clinical Informatics News Brief | A new computational model released by the HIV Resistance Response Database Initiative (RDI) tailors HIV drug cocktails to individual patients, without the need to perform expensive genotyping.

    Nov 26, 2013

  • Infinata Hosts Roundtable to Plan New Site Survey Product

    Clinical Informatics News | Of the pain points in clinical operations, Infinata believes site surveys are one of the worst: a crucial step to study start up that is often painful and slow. The company invited representatives from the sponsor, CRO, and site communities to Boston last month to discuss needs, ideas, and solutions to the challenge. The company plans to use the results of the discussion to fine tune their forthcoming site survey product that they expect to launch in February.

    Nov 22, 2013

  • Mysterious Virus Could Help Gauge Transplant Outcomes

    Clinical Informatics News Brief | The prevalence of the common but little-understood anellovirus tracked closely with levels of immune suppression in a study of transplant patients published today in Cell.

    Nov 21, 2013

  • When Should We Stop Screening for Cancer?

    Clinical Informatics News | It has long been acknowledged that cancer screens in the elderly may do more harm than good, but precise age cut-offs are difficult to estimate and validate. A team from the National Cancer Institute believes that better life expectancy tables, taking into account patients' comorbidity, could improve quality of life for elderly patients by directing cancer screens toward those most likely to benefit.

    Nov 19, 2013

  • TrialNetworks Co-Founder Nominated for Surgeon General

    Clinical Informatics News Brief | President Obama has nominated Vivek Murthy, co-founder and Chairman of TrialNetworks, to serve as the 19th US Surgeon General.

    Nov 18, 2013

  • CCMP Exploring $1.2B Sale of Medpace

    Reuters | Medpace, a CRO offering therapeutically specialized clinical development, is on the auction block according to Reuters. 

    Nov 15, 2013

  • Memorial Healthcare's Vendors Get VETTED

    Clinical Informatics News | You might be surprised how much fraud can flourish in the vendor networks of a large hospital system. Over the past year and a half, Florida's Memorial Healthcare System has used big data solutions to dig up fraud in its third-party contracts — with astonishing results.

    Nov 14, 2013

  • EHRs Should be Unregulated, Association Says

    Government Health IT | The Electronic Health Record Association has released a letter affirming that EHR systems should not be treated as medical devices and should remain unregulated by FDA.

    Nov 11, 2013

  • Coming Soon: The Best of Clinical Ops

    Clinical Informatics News | Clinical Informatics News is excited to announce that it is seeking submissions for the first Clinical Informatics News Best Practices Awards. This awards program seeks to recognize outstanding examples of applied strategic innovation—partnerships, deployments, and collaborations that manifestly improve the clinical trial process. The deadline for entry is December 16, 2013 and winners will be announced at the Summit for Clinical Ops Executives (SCOPE) in Miami in February 2014.

    Nov 11, 2013

  • Better-Targeted Clinical Test Cuts Antibiotic Use for Sore Throats

    University of Southampton | The FeverPAIN clinical test, when applied to patients complaining of sore throats, can offer greater precision in prescribing antibiotics without complicating clinicians' workloads.

    Nov 11, 2013

  • BMS Makes Cuts to Clinical Development/Ops

    Xconomy | Bristol-Myers Squibb is making cuts to the clinical development/operations group it acquired when it picked up ZymoGenetics in 2010.

    Nov 8, 2013

  • Covance, Pathoquest Collaborate on NGS Safety Platform

    Outsourcing Pharma | Covance and Pathoquest have signed an agreement to build an NGS-based biosafety assessment platform.

    Nov 7, 2013

  • Considering Compassionate Use

    New York Times | When it comes to the dying, some skip the full clinical trial process and take drugs offered as "compassionate use". But does that route rob us of valuable clinical information?

    Nov 5, 2013

  • Open Clinical Trials Data: Good for Pharma?

    TechDirt | There's been debate about whether clinical trials data should be made freely available. The European Medicines Agency had plans to release data, but AbbVie pharma objected.

    Nov 5, 2013

  • Taking on an Adaptive Dose Response Model

    Clinical Informatics News | Earlier this month, the European Medicines Agency (EMA) issued a qualification opinion on a statistical and modeling methodology for determining dose in clinical development.

    Oct 31, 2013

  • Building a Global Clinical Trials Network

    Clinical Informatics News  The idea came to Greg Koski while sitting in an airplane. “The entire world has come to recognize that the process that we've evolved for trying to get a new medical product—whether it's a drug, a device, or biologic—actually properly tested and reviewed, marketed, is fraught with enormous problems,” Koski says, “not the least of which, is the enormous inefficiency, redundancy in the process.”

    Oct 29, 2013

  • Highlights from the ASHG 2013 Annual Meeting - Implications for Clinical Practice

    Clinical Informatics News | With genetics moving confidently into the clinic, findings presented at the 2013 American Society of Human Genetics Meeting may have immediate clinical relevance. Here's what you might have missed.

    Oct 28, 2013

  • NIH Announces $79 Million in Clinical, Translational Science Awards

    Government Health-IT | The National Institutes of Health have announced $79 million in fiscal year 2013 funding to support 15 Institutional Clinical and Translational Science Awards (CTSA).

    Oct 23, 2013